Purity | > 95% of capped mRNA (depends on applied mRNA purification method) |
mRNA homogeneity | agarose gel & HPLC analysis |
dsRNA content | < 1-2% |
RNA concentration | > 1 mg/mL (or other requested by the Customer ) |
Optical purity (A260/A280) | ~2.0-2.2(+/- 0.2) (depending on mRNA sequence, presence of internal modifications and their frequency within the whole transcript) |
for mRNA-LNP: | |
Encapsulation Efficiency | > 80% |
Particle size | 50-150 nm |